Carissa Cole

Biochemical Pregnancies

Biochemical pregnancies are an early-stage miscarriage and one of the most common types. Unfortunately, it can take an emotional toll on the parents who are trying to conceive a child. In this paper, I go through some of the reasons that this event may occur. It is first important to understand the process of fertilization, implantation, and development of the conceptus. With an understanding, it is easier to grasp the complexities of pregnancy and why mistakes may occur during development. Early miscarriage can occur for a few different reasons. Research has found that most occur from chromosomal abnormalities, specifically aneuploidy and sperm DNA fragmentation. There is also evidence that there can be endometrial complications. The thickness of the endometrium plays a role in keeping the fertilized egg alive. Findings also suggest that implantation can determine if a biochemical pregnancy happens. The mother’s uterus can reject the implanting embryo, and there seems to be a preferred window of implantation that allows the conceptus to survive. Most interestingly, it has been found that women who undergo in-vitro fertilization are less likely to have an early miscarriage when compared to those who have a sporadic pregnancy. While there is some research dedicated to answering the question of why chemical pregnancies occur, there is not much dedicated to preventative measures. Evidence does suggest that there are a few, specifically preventing aneuploidy, but there are minimal resources dedicated to this research. Overall, biochemical pregnancies are an unfortunate occurrence that plagues many women, and because of this, more time and resources need to be dedicated to research on early pregnancy loss.

BIOL 499, Senior Capstone

Paul Allee

Womack 100

1:30 – 2 PM

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