Levi Dean

CRISPR
The discovery of DNA and its role in carrying genetic information was discovered in 1953. However, until recently scientists did not know that it could be altered. The development of CRISPR technology allows scientists to edit DNA sequences to alter how a gene functions. This discovery could lead to correcting hereditary diseases, which could potentially eradicate certain diseases indefinitely.
My capstone will describe how CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) works at the molecular level as well as its genome editing ability. I will start by introducing CRISPR, how it works, and how it has developed. From here I will introduce CRISPR’s genome editing abilities and its impact on the medical field such as correcting hereditary diseases. Furthermore, I have observed CRISPR’s effect on Zebra fish genomes in the Miller lab at the University of Oregon and I will share my experience from that. Since CRISPR technology allows scientists to edit DNA sequences to change or correct gene functionality, therefore changing an already developed person, some have found it to be unethical. I will end by discussing the potential ethical issues that CRISPR may have on society.
BIOL 499, Capstone
Paul Allee
P114
2 – 2:30 PM
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