Tag: McCluskey

Joshua McCluskey

Skeletal Muscle Soreness and Fatigue; Causes and Treatment

High intensity training, induces muscle fatigue, increases blood lactate levels, causes an accumulation of metabolites within the muscle body, and induces sensations of pain and decreased mobility following the exercise. In an effort to mitigate the feeling of strain on the body often we turn towards different recovery modalities; cryotherapy, myofascial release, and electrical stimulation. Many times these can have a perceived benefit while being administered which may not always be truly indicative of whether the modality has any efficacy. This review was aimed at addressing the objective benefits seen with each training modality, which encompasses how they affect muscle soreness, subjective feelings of fatigue prior to the next exercise, and biological markers and indicators for inflammation levels.

BIOL 499, Senior Capstone

Paul Allee

P114

11 – 11:30 AM

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Scholar Lunch

Come to L203 at noon. If you’re one of the first to arrive, you can have free pizza. The meal’s entertainment consists of five minute talks by representatives from majors and minors across campus. Speakers will take a single idea they learned from their major or minor coursework, explain it, explain why it’s useful or beautiful, and explain why they personally love it. Scheduled speakers:

  • Cameron Binaley, History
  • Grayson Rose Carmack, Psychology
  • Tanner Dean, English
  • Miranda Gutierrez, Spanish
  • Bradley Keller, Communication
  • Joshua McCluskey, Biology

L203

Noon – 1 PM

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Joshua McCluskey

Comparing the effects of different classes of medication in the management of hypertension 

The diagnosis of hypertension is common and treatment is frequently viewed as very simple. Treating hypertension takes more than just lowering the blood pressure of an individual. There are comorbidities that affect and are affected by the treatment of hypertension: kidney disease and cardiovascular disease. In this review we discuss the different preferences of using either Angiotensin Converting Enzyme (ACE) inhibitors, Calcium Channel blockers, Beta Blockers, and Diuretics when managing hypertension with the use of medications. It appears that Angiotensin Converting Enzyme (ACE) inhibitors were preferential to the management of kidney disease secondary to hypertension. Calcium channel blockers were additionally found to have an advantage with many cardiovascular diseases while beta blockers were also considered for cardiovascular issues including atrial fibrillation and tachycardia specifically. Beta blockers and Diuretics had minute differences in secondary management of cardiovascular disease and kidney disease when compared. 

CHEM 415, Biochemistry 

Heike McNeil 

P114 

11:30 AM – Noon 

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Joshua McCluskey

CRISPR

Clustered regularly interspaced short palindromic repeats, Crispr for short is a dna sequence that can be used by the cas9 system of rna guided nucleases that effectively cleaves the section of dna containing a specific genome to repair or alter that specified genome. The crispr system is an adaptive immune system that is used and regulated by microbes and cells to defend against foreign substances and viruses by recognizing and eliminating the specific dna sequence associated with that virus. Most crispr systems contain 20-24 regularly spaced palindromic bases separated by spacers. The crispr cassettes are found in almost every archeon and almost half of bacteria studied. This provides a wide range of uses for the cas9 system and adds to the versatility of the system. We can use this system to replicate and code for specific genomes in animals and further understand how their traits are coded and replicated, we can create complex models for human inherited diseases or cancers, it can also be used to pinpoint the cause for underlying genetic processes by genome wide screening of the dna in any human cell. The origin of crispr however is the most intriguing aspect of the system. Being a biological system that was discovered and not a human engineered system, the origin is not entirely clear.

BIOL 200, General Biology

Paul Allee

P003

1:30 – 2:00 PM

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Joshua McCluskey

Applied Calculus in Medicine

Medicine utilizes calculus in many ways, through the use of derivatives we can optimize uses of material as well as calculate the effect of a surgery. angioplasty uses calculus to calculate the effect of widening an artery to increase blood flow. Calculus lets us know definitively to what extent the blood flow will increase. we can also use calculus in a crime scene. determining the time of death.

MATH 251, Calculus I

Connie Wilmarth

Banquet Room, Poster #8

10 AM – Noon

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